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Effects of Novel Dual GIP and GLP-1 Receptor Agonist Tirzepatide on Biomarkers of Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes
Author(s) -
Mark L. Hartman,
Arun J. Sanyal,
Rohit Loomba,
Jonathan M. Wilson,
Amir Nikooienejad,
Ross Bray,
Chrisanthi A. Karanikas,
Kevin L. Duffin,
Deborah Robins,
Axel Haupt
Publication year - 2020
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc19-1892
Subject(s) - medicine , nonalcoholic steatohepatitis , agonist , diabetes mellitus , type 2 diabetes , glucagon like peptide 1 receptor , endocrinology , receptor , disease , nonalcoholic fatty liver disease , fatty liver
To determine the effect of tirzepatide, a dual agonist of glucose-dependent insulinotropic polypeptide and glucagon-like peptide 1 receptors, on biomarkers of nonalcoholic steatohepatitis (NASH) and fibrosis in patients with type 2 diabetes mellitus (T2DM).

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