Mediation of the Effect of Glycemia on the Risk of CVD Outcomes in Type 1 Diabetes: The DCCT/EDIC Study | Zendy

Ionut Bebu | Zendy; Barbara H. Braffett | Zendy; Trevor J. Orchard | Zendy; Gayle M. Lorenzi | Zendy; John M. Lachin | Zendy

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Mediation of the Effect of Glycemia on the Risk of CVD Outcomes in Type 1 Diabetes: The DCCT/EDIC Study

Author(s) -

Ionut Bebu,

Barbara H. Braffett,

Trevor J. Orchard,

Gayle M. Lorenzi,

John M. Lachin

Publication year - 2019

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc18-1613

Subject(s) - medicine , type 1 diabetes , diabetes mellitus , mediation , type 2 diabetes , endocrinology , political science , law

The Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) study has demonstrated the major role of hyperglycemia as a risk factor for clinical cardiovascular outcomes in type 1 diabetes (T1D). We assessed whether and to what extent the effect of glycemia is mediated by other established cardiovascular disease (CVD) risk factors.

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