C-Peptide Decline in Type 1 Diabetes Has Two Phases: An Initial Exponential Fall and a Subsequent Stable Phase | Zendy

Beverley M. Shields | Zendy; Timothy J. McDonald | Zendy; Richard A. Oram | Zendy; Anita Hill | Zendy; Michelle Hudson | Zendy; Pia Leete | Zendy; Ewan R. Pearson | Zendy; Sarah J. Richardson | Zendy; Noel G. Morgan | Zendy; Andrew T. Hattersley | Zendy; Bart O. Roep | Zendy; Timothy Tree | Zendy; S. Hammersley | Zendy; R. F. Bolt | Zendy

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C-Peptide Decline in Type 1 Diabetes Has Two Phases: An Initial Exponential Fall and a Subsequent Stable Phase

Author(s) -

Beverley M. Shields,

Timothy J. McDonald,

Richard A. Oram,

Anita Hill,

Michelle Hudson,

Pia Leete,

Ewan R. Pearson,

Sarah J. Richardson,

Noel G. Morgan,

Andrew T. Hattersley,

Bart O. Roep,

Timothy Tree,

S. Hammersley,

R. F. Bolt

Publication year - 2018

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc18-0465

Subject(s) - medicine , diabetes mellitus , c peptide , type 1 diabetes , longitudinal study , creatinine , demography , peptide , endocrinology , biology , pathology , biochemistry , sociology

The decline in C-peptide in the 5 years after diagnosis of type 1 diabetes has been well studied, but little is known about the longer-term trajectory. We aimed to examine the association between log-transformed C-peptide levels and the duration of diabetes up to 40 years after diagnosis.

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