Accelerated Progression to Type 1 Diabetes in the Presence of HLA-A*24 and -B*18 Is Restricted to Multiple Islet Autoantibody–Positive Individuals With Distinct HLA-DQ and Autoantibody Risk Profiles | Zendy

Else M. Balke | Zendy; Eric V. Balti | Zendy; Bart Van Der Auwera | Zendy; Ilse Weets | Zendy; Olivier Costa | Zendy; Simke Demeester | Zendy; Pascale Abrams | Zendy; Kristina Casteels | Zendy; M. Coeckelberghs | Zendy; Sylvie Tenoutasse | Zendy; Bart Keymeulen | Zendy; Daniël Pipeleers | Zendy; Frans Gorus | Zendy

Open Access

Accelerated Progression to Type 1 Diabetes in the Presence of HLA-A*24 and -B*18 Is Restricted to Multiple Islet Autoantibody–Positive Individuals With Distinct HLA-DQ and Autoantibody Risk Profiles

Author(s) -

Else M. Balke,

Eric V. Balti,

Bart Van Der Auwera,

Ilse Weets,

Olivier Costa,

Simke Demeester,

Pascale Abrams,

Kristina Casteels,

M. Coeckelberghs,

Sylvie Tenoutasse,

Bart Keymeulen,

Daniël Pipeleers,

Frans Gorus

Publication year - 2018

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc17-2462

Subject(s) - medicine , autoantibody , islet , type 1 diabetes , human leukocyte antigen , diabetes mellitus , immunology , type 2 diabetes , insulitis , endocrinology , antibody , antigen

We investigated the effect of HLA class I risk alleles on disease progression in various phases of subclinical islet autoimmunity in first-degree relatives of patients with type 1 diabetes.

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