Effects of Liraglutide on Weight Loss, Fat Distribution, and β-Cell Function in Obese Subjects With Prediabetes or Early Type 2 Diabetes | Zendy

Francesca Santilli | Zendy; Paola Simeone | Zendy; Maria Teresa Guagnano | Zendy; Marika Leo | Zendy; Marica Tina Maccarone | Zendy; Augusto Di Castelnuovo | Zendy; Cristina Sborgia | Zendy; Riccardo C. Bonadonna | Zendy; E Angelucci | Zendy; Virginia Federico | Zendy; Stefano Cianfarani | Zendy; Lamberto Manzoli | Zendy; Giovanni Davı̀ | Zendy; Armando Tartaro | Zendy; Agostino Consoli | Zendy

Open Access

Effects of Liraglutide on Weight Loss, Fat Distribution, and β-Cell Function in Obese Subjects With Prediabetes or Early Type 2 Diabetes

Author(s) -

Francesca Santilli,

Paola Simeone,

Maria Teresa Guagnano,

Marika Leo,

Marica Tina Maccarone,

Augusto Di Castelnuovo,

Cristina Sborgia,

Riccardo C. Bonadonna,

E Angelucci,

Virginia Federico,

Stefano Cianfarani,

Lamberto Manzoli,

Giovanni Davı̀,

Armando Tartaro,

Agostino Consoli

Publication year - 2017

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc17-0589

Subject(s) - medicine , liraglutide , prediabetes , type 2 diabetes , weight loss , diabetes mellitus , endocrinology , obesity

Obesity is associated with an increased risk of type 2 diabetes and cardiovascular complications. The risk depends significantly on adipose tissue distribution. Liraglutide, a glucagon-like peptide 1 analog, is associated with weight loss, improved glycemic control, and reduced cardiovascular risk. We determined whether an equal degree of weight loss by liraglutide or lifestyle changes has a different impact on subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) in obese subjects with prediabetes or early type 2 diabetes.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research