Plasma Concentrations of Afamin Are Associated With Prevalent and Incident Type 2 Diabetes: A Pooled Analysis in More Than 20,000 Individuals | Zendy

Barbara Kollerits | Zendy; Claudia Lamina | Zendy; Cornelia Huth | Zendy; Pedro MarquesVidal | Zendy; Stefan Kiechl | Zendy; Ilkka Seppälä | Zendy; Jackie A. Cooper | Zendy; Steven C. Hunt | Zendy; Christa Meisinger | Zendy; Christian Herder | Zendy; Ludmilla Kedenko | Zendy; Johann Willeit | Zendy; Barbara Thorand | Zendy; Doreen Dähnhardt | Zendy; Doris Stöckl | Zendy; Karin Willeit | Zendy; Michael Roden | Zendy; Wolfgang Rathmann | Zendy; Bernhard Paulweber | Zendy; Annette Peters | Zendy; Mika Kähönen | Zendy; Terho Lehtimäki | Zendy; Olli T. Raitakari | Zendy; Steve E. Humphries | Zendy; Péter Vollenweider | Zendy; Hans Dieplinger | Zendy; Florian Kronenberg | Zendy

Open Access

Plasma Concentrations of Afamin Are Associated With Prevalent and Incident Type 2 Diabetes: A Pooled Analysis in More Than 20,000 Individuals

Author(s) -

Barbara Kollerits,

Claudia Lamina,

Cornelia Huth,

Pedro MarquesVidal,

Stefan Kiechl,

Ilkka Seppälä,

Jackie A. Cooper,

Steven C. Hunt,

Christa Meisinger,

Christian Herder,

Ludmilla Kedenko,

Johann Willeit,

Barbara Thorand,

Doreen Dähnhardt,

Doris Stöckl,

Karin Willeit,

Michael Roden,

Wolfgang Rathmann,

Bernhard Paulweber,

Annette Peters,

Mika Kähönen,

Terho Lehtimäki,

Olli T. Raitakari,

Steve E. Humphries,

Péter Vollenweider,

Hans Dieplinger,

Florian Kronenberg

Publication year - 2017

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc17-0201

Subject(s) - medicine , prediabetes , type 2 diabetes , diabetes mellitus , incidence (geometry) , odds ratio , prospective cohort study , cohort study , gastroenterology , endocrinology , physics , optics

The human vitamin E-binding glycoprotein afamin is primarily expressed in the liver and has been associated with prevalent and incident metabolic syndrome. These data were in line with observations in transgenic mice. We thus investigated whether afamin concentrations are associated with prediabetes, type 2 diabetes, and insulin resistance (IR).

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