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Fetal Outcomes After Diabetic Ketoacidosis During Pregnancy
Author(s) -
Fritha Morrison,
Maryam Movassaghian,
Ellen W. Seely,
Ashley Curran,
Maria Shubina,
Emma Morton-Eggleston,
Chloe Zera,
Jeffrey L. Ecker,
Florence M. Brown,
Alexander Turchin
Publication year - 2017
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc17-0186
Subject(s) - medicine , diabetic ketoacidosis , diabetes mellitus , pregnancy , obstetrics , ketoacidosis , fetus , endocrinology , type 1 diabetes , genetics , biology
Historical literature reports risk of fetal demise after diabetic ketoacidosis (DKA) in pregnancy as high as 25–60% (1,2). However, estimates have generally been based on small sample sizes, with limited investigation of other fetal outcomes or risk factors associated with poor fetal outcomes. We aimed to provide an updated assessment of the incidence and risk factors for fetal demise and other adverse outcomes in women with DKA during pregnancy.This retrospective cohort study included pregnancies between 1996 and 2015 with at least one DKA event in women with type 1 diabetes at one of three teaching hospitals in Boston. Data were collected through medical record review. Pregnancies were excluded if information on birth status (live or demise) and gestational age at birth or demise were unknown.Among the 77 DKA events in 64 pregnancies in 62 women included in the study, fetal demise, preterm …

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