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Long-term Benefits of Intensive Glucose Control for Preventing End-Stage Kidney Disease: ADVANCE-ON
Author(s) -
Muh Geot Wong,
Vlado Perkovic,
John Chalmers,
Mark Woodward,
Qiang Li,
Mark E. Cooper,
Pavel Hamet,
Stephen Harrap,
Simon Heller,
Stephen MacMahon,
Giuseppe Mancia,
Michel Marre,
David R. Matthews,
Bruce Neal,
Neil R Poulter,
Anthony Rodgers,
Bryan Williams,
Sophia Zoungas
Publication year - 2016
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc15-2322
Subject(s) - medicine , kidney disease , diabetes mellitus , dialysis , hazard ratio , intensive care medicine , type 2 diabetes , randomized controlled trial , cause of death , disease , endocrinology , confidence interval
The Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation (ADVANCE) trial reported that intensive glucose control prevents end-stage kidney disease (ESKD) in patients with type 2 diabetes, but uncertainty about the balance between risks and benefits exists. Here, we examine the long-term effects of intensive glucose control on risk of ESKD and other outcomes.

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