Brain and White Matter Hyperintensity Volumes After 10 Years of Random Assignment to Lifestyle Intervention | Zendy

Mark A. Espeland | Zendy; Kirk I. Erickson | Zendy; Rebecca H. Neiberg | Zendy; John M. Jakicic | Zendy; Thomas A. Wadden | Zendy; Rena R. Wing | Zendy; Lisa Desiderio | Zendy; Güray Erus | Zendy; M. Ani Hsieh | Zendy; Christos Davatzikos | Zendy; Barbara J. Maschak-Carey | Zendy; Paul J. Laurienti | Zendy; Kathryn E. Demos | Zendy; R. Nick Bryan | Zendy

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Brain and White Matter Hyperintensity Volumes After 10 Years of Random Assignment to Lifestyle Intervention

Author(s) -

Mark A. Espeland,

Kirk I. Erickson,

Rebecca H. Neiberg,

John M. Jakicic,

Thomas A. Wadden,

Rena R. Wing,

Lisa Desiderio,

Güray Erus,

M. Ani Hsieh,

Christos Davatzikos,

Barbara J. Maschak-Carey,

Paul J. Laurienti,

Kathryn E. Demos,

R. Nick Bryan

Publication year - 2016

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc15-2230

Subject(s) - medicine , hyperintensity , overweight , diabetes mellitus , brain structure and function , type 2 diabetes , brain size , randomized controlled trial , weight loss , physical therapy , cognition , magnetic resonance imaging , obesity , endocrinology , psychiatry , radiology

Type 2 diabetes increases the accumulation of brain white matter hyperintensities and loss of brain tissue. Behavioral interventions to promote weight loss through dietary changes and increased physical activity may delay these adverse consequences. We assessed whether participation in a successful 10-year lifestyle intervention was associated with better profiles of brain structure.

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