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A1C Combined With Glycated Albumin Improves Detection of Prediabetes in Africans: The Africans in America Study
Author(s) -
Anne E. Sumner,
Michelle Duong,
Paola C. Aldana,
Madia Ricks,
Marshall K. TullochReid,
Jay N. Lozier,
Stephanie T. Chung,
David B. Sacks
Publication year - 2015
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc15-1699
Subject(s) - fructosamine , prediabetes , medicine , glycated hemoglobin , diabetes mellitus , endocrinology , type 2 diabetes , gastroenterology
Slowing the diabetes epidemic in Africa requires improved detection of prediabetes. A1C, a form of glycated hemoglobin A, is recommended for diagnosing prediabetes. The glycated proteins, fructosamine and glycated albumin (GA), are hemoglobin-independent alternatives to A1C, but their efficacy in Africans is unknown. Our goals were to determine the ability of A1C, fructosamine, and GA to detect prediabetes in U.S.-based Africans and the value of combining A1C with either fructosamine or GA.

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