A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults | Zendy

Richard A. Oram | Zendy; Kashyap Patel | Zendy; Anita Hill | Zendy; Beverley M. Shields | Zendy; Timothy J. McDonald | Zendy; Angus G. Jones | Zendy; Andrew T. Hattersley | Zendy; Michael N. Weedon | Zendy

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A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults

Author(s) -

Richard A. Oram,

Kashyap Patel,

Anita Hill,

Beverley M. Shields,

Timothy J. McDonald,

Angus G. Jones,

Andrew T. Hattersley,

Michael N. Weedon

Publication year - 2015

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc15-1111

Subject(s) - medicine , type 1 diabetes , type 2 diabetes , diabetes mellitus , young adult , single nucleotide polymorphism , area under the curve , endocrinology , genotype , genetics , biology , gene

With rising obesity, it is becoming increasingly difficult to distinguish between type 1 diabetes (T1D) and type 2 diabetes (T2D) in young adults. There has been substantial recent progress in identifying the contribution of common genetic variants to T1D and T2D. We aimed to determine whether a score generated from common genetic variants could be used to discriminate between T1D and T2D and also to predict severe insulin deficiency in young adults with diabetes.

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