Subclinical Atherosclerosis Is Inversely Associated With Gray Matter Volume in African Americans With Type 2 Diabetes | Zendy

Barry I. Freedman | Zendy; Jasmin Divers | Zendy; Christopher T. Whitlow | Zendy; Donald W. Bowden | Zendy; Nicholette D. Palmer | Zendy; Stephen M. Smith | Zendy; Jianzhao Xu | Zendy; Thomas C. Register | Zendy; J. Jeffrey Carr | Zendy; Benjamin Wagner | Zendy; Jeff D. Williamson | Zendy; Kaycee M. Sink | Zendy; Joseph A. Maldjian | Zendy

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Subclinical Atherosclerosis Is Inversely Associated With Gray Matter Volume in African Americans With Type 2 Diabetes

Author(s) -

Barry I. Freedman,

Jasmin Divers,

Christopher T. Whitlow,

Donald W. Bowden,

Nicholette D. Palmer,

Stephen M. Smith,

Jianzhao Xu,

Thomas C. Register,

J. Jeffrey Carr,

Benjamin Wagner,

Jeff D. Williamson,

Kaycee M. Sink,

Joseph A. Maldjian

Publication year - 2015

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc15-1035

Subject(s) - medicine , diabetes mellitus , subclinical infection , type 2 diabetes , gray (unit) , cardiology , endocrinology , nuclear medicine

Relative to European Americans, African Americans manifest lower levels of computed tomography-based calcified atherosclerotic plaque (CP), a measure of subclinical cardiovascular disease (CVD). Potential relationships between CP and cerebral structure are poorly defined in the African American population. We assessed associations among glycemic control, inflammation, and CP with cerebral structure on MRI and with cognitive performance in 268 high-risk African Americans with type 2 diabetes.

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