Reduced Lower-Limb Muscle Strength and Volume in Patients With Type 2 Diabetes in Relation to Neuropathy, Intramuscular Fat, and Vitamin D Levels | Zendy

Monirah M. Almurdhi | Zendy; Neil D. Reeves | Zendy; Frank L. Bowling | Zendy; Andrew J.M. Boulton | Zendy; Maria Jeziorska | Zendy; Rayaz A. Malik | Zendy

Open Access

Reduced Lower-Limb Muscle Strength and Volume in Patients With Type 2 Diabetes in Relation to Neuropathy, Intramuscular Fat, and Vitamin D Levels

Author(s) -

Monirah M. Almurdhi,

Neil D. Reeves,

Frank L. Bowling,

Andrew J.M. Boulton,

Maria Jeziorska,

Rayaz A. Malik

Publication year - 2016

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc15-0995

Subject(s) - medicine , ankle , muscle weakness , muscle atrophy , plantar flexion , diabetes mellitus , atrophy , vitamin d and neurology , intramuscular fat , peripheral neuropathy , weakness , type 2 diabetes , muscle strength , endocrinology , surgery , biochemistry , chemistry

Muscle weakness and atrophy of the lower limbs may develop in patients with diabetes, increasing their risk of falls. The underlying basis of these abnormalities has not been fully explained. The aim of this study was to objectively quantify muscle strength and size in patients with type 2 diabetes mellitus (T2DM) in relation to the severity of neuropathy, intramuscular noncontractile tissue (IMNCT), and vitamin D deficiency.

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