Alogliptin, a Dipeptidyl Peptidase 4 Inhibitor, Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A) | Zendy

Tomoya Mita | Zendy; Naoto Katakami | Zendy; Hidenori Yoshii | Zendy; Tomio Onuma | Zendy; Hideaki Kaneto | Zendy; Takeshi Osonoi | Zendy; Toshihiko Shiraiwa | Zendy; Keisuke Kosugi | Zendy; Yutaka Umayahara | Zendy; Tsunehiko Yamamoto | Zendy; Hiroki Yokoyama | Zendy; Nobuichi Kuribayashi | Zendy; Hideaki Jinnouchi | Zendy; Masahiko Gosho | Zendy; Iichiro Shimomura | Zendy; Hirotaka Watada | Zendy

Open Access

Alogliptin, a Dipeptidyl Peptidase 4 Inhibitor, Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A)

Author(s) -

Tomoya Mita,

Naoto Katakami,

Hidenori Yoshii,

Tomio Onuma,

Hideaki Kaneto,

Takeshi Osonoi,

Toshihiko Shiraiwa,

Keisuke Kosugi,

Yutaka Umayahara,

Tsunehiko Yamamoto,

Hiroki Yokoyama,

Nobuichi Kuribayashi,

Hideaki Jinnouchi,

Masahiko Gosho,

Iichiro Shimomura,

Hirotaka Watada

Publication year - 2015

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc15-0781

Subject(s) - alogliptin , medicine , dipeptidyl peptidase 4 inhibitor , diabetes mellitus , dipeptidyl peptidase 4 , type 2 diabetes mellitus , type 2 diabetes , hypoglycemia , clinical endpoint , gastroenterology , cardiology , endocrinology , urology , randomized controlled trial

Recent experimental studies have shown that dipeptidyl peptidase 4 (DPP-4) inhibitors have antiatherosclerotic benefits in glucagon-like peptide 1-dependent and -independent manners. The current study investigated the effects of alogliptin, a DPP-4 inhibitor, on the progression of carotid atherosclerosis in patients with type 2 diabetes mellitus (T2DM).

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