Gastric Bypass Surgery in Severely Obese Women With Type 1 Diabetes: Anthropometric and Cardiometabolic Effects at 1 and 5 Years Postsurgery | Zendy

Roeland J.W. Middelbeek | Zendy; Tamarra JamesTodd | Zendy; Jerry D. Cavallerano | Zendy; D. Schlossman | Zendy; MaryElizabeth Patti | Zendy; Florence M. Brown | Zendy

Open Access

Gastric Bypass Surgery in Severely Obese Women With Type 1 Diabetes: Anthropometric and Cardiometabolic Effects at 1 and 5 Years Postsurgery

Author(s) -

Roeland J.W. Middelbeek,

Tamarra JamesTodd,

Jerry D. Cavallerano,

D. Schlossman,

MaryElizabeth Patti,

Florence M. Brown

Publication year - 2015

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc15-0396

Subject(s) - medicine , type 2 diabetes , diabetes mellitus , gastric bypass surgery , glycemic , obesity , surgery , type 1 diabetes , anthropometry , weight loss , gastric bypass , endocrinology

While the benefits of gastric bypass (GB) surgery in type 2 diabetes are well established, few studies have evaluated the long-term effects of GB in patients with type 1 diabetes (1,2), and these studies demonstrate conflicting effects on glycemic control. This is clinically important given the increasing prevalence of obesity in patients with type 1 diabetes (3). We studied 10 severely obese women with confirmed type 1 diabetes, as previously described (4), and evaluated outcomes prior to GB and at 1 and 5 years following surgery. Mean age at GB was 39.6 ± 8.4 years, mean duration of type 1 diabetes 24.6 ± 10.1 years, and mean age at diagnosis 16.0 ± 8.3 years. Six subjects used continuous subcutaneous insulin infusion.BMI decreased by 33% from baseline at 1 year postoperatively (from 43.5 ± 7.5 to 29.3 ± 5.4 kg/m2, P < 0.0001) but …

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