Predictive Low-Glucose Insulin Suspension Reduces Duration of Nocturnal Hypoglycemia in Children Without Increasing Ketosis | Zendy

Bruce A. Buckingham | Zendy; Dan Raghinaru | Zendy; Fraser Cameron | Zendy; B. Wayne Bequette | Zendy; H. Peter Chase | Zendy; David M. Maahs | Zendy; Robert H. Slover | Zendy; R. Paul Wadwa | Zendy; Darrell M. Wilson | Zendy; Trang T. Ly | Zendy; Tandy Aye | Zendy; Irene Hramiak | Zendy; Cheril Clarson | Zendy; Robert Stein | Zendy; Patricia Gallego | Zendy; John Lum | Zendy; Judy Sibayan | Zendy; Craig Kollman | Zendy; Roy W. Beck | Zendy

Open Access

Predictive Low-Glucose Insulin Suspension Reduces Duration of Nocturnal Hypoglycemia in Children Without Increasing Ketosis

Author(s) -

Bruce A. Buckingham,

Dan Raghinaru,

Fraser Cameron,

B. Wayne Bequette,

H. Peter Chase,

David M. Maahs,

Robert H. Slover,

R. Paul Wadwa,

Darrell M. Wilson,

Trang T. Ly,

Tandy Aye,

Irene Hramiak,

Cheril Clarson,

Robert Stein,

Patricia Gallego,

John Lum,

Judy Sibayan,

Craig Kollman,

Roy W. Beck

Publication year - 2015

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc14-3053

Subject(s) - medicine , hypoglycemia , glycemic , morning , ketosis , diabetes mellitus , type 1 diabetes , insulin , endocrinology , randomized controlled trial , pediatrics

Nocturnal hypoglycemia can cause seizures and is a major impediment to tight glycemic control, especially in young children with type 1 diabetes. We conducted an in-home randomized trial to assess the efficacy and safety of a continuous glucose monitor-based overnight predictive low-glucose suspend (PLGS) system.

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