n-3 Fatty Acids Attenuate the Risk of Diabetes Associated With Elevated Serum Nonesterified Fatty Acids: The Multi-Ethnic Study of Atherosclerosis | Zendy

Brian T. Steffen | Zendy; Lyn M. Steffen | Zendy; Xia Zhou | Zendy; Pamela Ouyang | Zendy; Natalie L. Weir | Zendy; Michael Y. Tsai | Zendy

Open Access

n-3 Fatty Acids Attenuate the Risk of Diabetes Associated With Elevated Serum Nonesterified Fatty Acids: The Multi-Ethnic Study of Atherosclerosis

Author(s) -

Brian T. Steffen,

Lyn M. Steffen,

Xia Zhou,

Pamela Ouyang,

Natalie L. Weir,

Michael Y. Tsai

Publication year - 2015

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc14-1919

Subject(s) - medicine , type 2 diabetes , endocrinology , diabetes mellitus , nefa , hazard ratio , quartile , insulin , confidence interval

Chronically high nonesterified fatty acids (NEFAs) are a marker of metabolic dysfunction and likely increase risk of type 2 diabetes. By comparison, n-3 fatty acids (FAs) have been shown to have various health benefits and may protect against disease development. In 5,697 participants of the Multi-Ethnic Study of Atherosclerosis (MESA), we examined whether serum levels of NEFAs relate to risk of incident type 2 diabetes and further tested whether plasma n-3 FA levels may interact with this relation.

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