Demonstration of an Intrinsic Relationship Between Endogenous C-Peptide Concentration and Determinants of Glycemic Control in Type 1 Diabetes Following Islet Transplantation | Zendy

Augustin Brooks | Zendy; Richard A. Oram | Zendy; Philip Home | Zendy; Nick Steen | Zendy; James Shaw | Zendy

Open Access

Demonstration of an Intrinsic Relationship Between Endogenous C-Peptide Concentration and Determinants of Glycemic Control in Type 1 Diabetes Following Islet Transplantation

Author(s) -

Augustin Brooks,

Richard A. Oram,

Philip Home,

Nick Steen,

James Shaw

Publication year - 2014

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc14-1656

Subject(s) - medicine , glycemic , islet , c peptide , transplantation , endocrinology , diabetes mellitus , type 1 diabetes , hypoglycemia , insulin , peptide , biochemistry , biology

Maintenance of endogenous pancreatic β-cell function could be an important goal in the management of type 1 diabetes. However, the impact of stimulated C-peptide level on overall glycemic control is unknown. The relationship between C-peptide and parameters of glucose control was therefore characterized in a cohort with rapidly changing β-cell function following islet transplantation.

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