Spatial Patterns of Structural Brain Changes in Type 2 Diabetic Patients and Their Longitudinal Progression With Intensive Control of Blood Glucose | Zendy

Güray Erus | Zendy; Harsha Battapady | Zendy; Tianhao Zhang | Zendy; James Lovato | Zendy; Michael E. Miller | Zendy; Jeff D. Williamson | Zendy; Lenore J. Launer | Zendy; R. Nick Bryan | Zendy; Christos Davatzikos | Zendy

Open Access

Spatial Patterns of Structural Brain Changes in Type 2 Diabetic Patients and Their Longitudinal Progression With Intensive Control of Blood Glucose

Author(s) -

Güray Erus,

Harsha Battapady,

Tianhao Zhang,

James Lovato,

Michael E. Miller,

Jeff D. Williamson,

Lenore J. Launer,

R. Nick Bryan,

Christos Davatzikos

Publication year - 2014

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc14-1196

Subject(s) - medicine , glycemic , diabetes mellitus , brain size , type 1 diabetes , type 2 diabetes , white matter , voxel based morphometry , voxel , longitudinal study , endocrinology , magnetic resonance imaging , pathology , radiology

Understanding the effect of diabetes as well as of alternative treatment strategies on cerebral structure is critical for the development of targeted interventions against accelerated neurodegeneration in type 2 diabetes. We investigated whether diabetes characteristics were associated with spatially specific patterns of brain changes and whether those patterns were affected by intensive versus standard glycemic treatment.

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