Open AccessImpact of Islet Autoimmunity on the Progressive β-Cell Functional Decline in Type 2 Diabetes
Author(s) -
Barbara BrooksWorrell,
Edward J. Boyko,
Jerry P. Palmer
Publication year - 2014
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc14-0961
Subject(s) - autoimmunity , islet , medicine , autoantibody , endocrinology , type 1 diabetes , diabetes mellitus , insulinoma , immunology , immune system , insulin , antibody
Cross-sectional studies have suggested that islet autoimmunity may be more prevalent in type 2 diabetes (T2D) than previously appreciated and may contribute to the progressive decline in β-cell function. In this study, we longitudinally evaluated the effect of islet autoimmune development on the progressive β-cell dysfunction in T2D patients.
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