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Early Childhood Gut Microbiomes Show Strong Geographic Differences Among Subjects at High Risk for Type 1 Diabetes
Author(s) -
Kaisa Kemppainen,
Alexandria N. Ardissone,
Austin G. DavisRichardson,
Jennie R. Fagen,
K.A. Gano,
Luis LeónNovelo,
Kendra Vehik,
George Casella,
Olli Simell,
Anette G. Ziegler,
Marian Rewers,
Åke Lernmark,
William Hagopian,
JinXiong She,
Jeffrey P. Krischer,
Beena Akolkar,
Desmond Schatz,
Mark A. Atkinson,
Eric W. Triplett
Publication year - 2014
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc14-0850
Subject(s) - microbiome , medicine , type 2 diabetes , dysbiosis , diabetes mellitus , human leukocyte antigen , gut microbiome , population , type 1 diabetes , immunology , bioinformatics , gut flora , environmental health , biology , endocrinology , antigen
Gut microbiome dysbiosis is associated with numerous diseases, including type 1 diabetes. This pilot study determines how geographical location affects the microbiome of infants at high risk for type 1 diabetes in a population of homogenous HLA class II genotypes.

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