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Adipose Tissue, Muscle, and Function: Potential Mediators of Associations Between Body Weight and Mortality in Older Adults With Type 2 Diabetes
Author(s) -
Rachel A. Murphy,
Ilse Reinders,
Melissa E. Garcia,
Guðný Eiríksdóttir,
Lenore J. Launer,
Rafn Benediktsson,
Vilmundur Guðnason,
Pálmi V. Jónsson,
Tamara B. Harris
Publication year - 2014
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc14-0293
Subject(s) - medicine , overweight , hazard ratio , adipose tissue , diabetes mellitus , proportional hazards model , type 2 diabetes , obesity , body mass index , obesity paradox , endocrinology , confidence interval
Studies in type 2 diabetes report both increased mortality for normal weight and no evidence of an obesity paradox. We aimed to examine whether adipose tissue, muscle size, and physical function, which are known to vary by weight, mediate associations between BMI and mortality.

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