Basal Insulin Peglispro Demonstrates Preferential Hepatic Versus Peripheral Action Relative to Insulin Glargine in Healthy Subjects
Author(s) -
Robert R. Henry,
Sunder Mudaliar,
Theodore P. Ciaraldi,
Debra Armstrong,
P. Burke,
Jeremy Pettus,
Parag Garhyan,
Siak Leng Choi,
Scott J. Jacober,
Mary Pat Knadler,
Eric Chen Quin Lam,
Melvin Prince,
Namrata Bose,
Niels Pörksen,
Vikram Sinha,
Helle Linnebjerg
Publication year - 2014
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc14-0210
Subject(s) - insulin glargine , medicine , endocrinology , insulin , basal (medicine) , basal insulin , insulin analog , crossover study , diabetes mellitus , stimulation , type 2 diabetes , human insulin , hypoglycemia , placebo , alternative medicine , pathology
We evaluated the endogenous glucose production (EGP) and glucose disposal rate (GDR) over a range of doses of basal insulin peglispro (BIL) and insulin glargine in healthy subjects.
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