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Metabolic Syndrome, Prediabetes, and Brain Abnormalities on MRI in Patients With Manifest Arterial Disease: The SMART-MR Study
Author(s) -
A.M. Tiehuis,
Yolanda van der Graaf,
W.P.T.M. Mali,
Koen L. Vincken,
Majon Muller,
Mirjam I. Geerlings
Publication year - 2014
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc14-0154
Subject(s) - medicine , prediabetes , metabolic syndrome , diabetes mellitus , hypertriglyceridemia , hyperintensity , cardiology , brain size , abdominal obesity , disease , obesity , type 2 diabetes , endocrinology , magnetic resonance imaging , radiology , cholesterol , triglyceride
Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors leading to atherosclerosis and diabetes. Diabetes is associated with both structural and functional abnormalities of the brain. MetS, even before diabetes is diagnosed, may also predispose to cerebral changes, probably through shared mechanisms. We examined the association of MetS with cerebral changes in patients with manifest arterial disease.

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