Circulating Concentrations of Soluble Receptor for AGE Are Associated With Age and AGER Gene Polymorphisms in Children With Newly Diagnosed Type 1 Diabetes
Author(s) -
Kirsi M. Salonen,
Samppa Ryhänen,
Josephine M. Forbes,
Taina Härkönen,
Jorma Ilonen,
AnttiPekka Laine,
PerHenrik Groop,
Mikael Knip
Publication year - 2014
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc13-3049
Subject(s) - medicine , diabetes mellitus , endocrinology , single nucleotide polymorphism , genotype , type 1 diabetes , type 2 diabetes , glycation , population , diabetic ketoacidosis , haplotype , gastroenterology , genetics , gene , biology , environmental health
We analyzed the relationship among soluble receptor for advanced glycation end products (sRAGEs), the clinical phenotype, HLA genotype, and risk-associated single nucleotide polymorphisms (SNPs) in the AGER gene in a large population of Finnish children with newly diagnosed type 1 diabetes.
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