HDL-C and HDL-C/ApoA-I Predict Long-Term Progression of Glycemia in Established Type 2 Diabetes
Author(s) -
Boris Waldman,
Alicia J. Jenkins,
Timothy M. E. Davis,
MarjaRiitta Taskinen,
Russell Scott,
Rachel O’Connell,
Val Gebski,
M. Ng,
Anthony Keech
Publication year - 2014
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc13-2738
Subject(s) - medicine , insulin resistance , endocrinology , type 2 diabetes , glycemic , fenofibrate , insulin , apolipoprotein b , diabetes mellitus , hazard ratio , cholesterol , confidence interval
Low HDL cholesterol (HDL-C) and small HDL particle size may directly promote hyperglycemia. We evaluated associations of HDL-C, apolipoprotein A-I (apoA-I), and HDL-C/apoA-I with insulin secretion, insulin resistance, HbA1c, and long-term glycemic deterioration, reflected by initiation of pharmacologic glucose control.
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