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Second-Line Agents for Glycemic Control for Type 2 Diabetes: Are Newer Agents Better?
Author(s) -
Yuanhui Zhang,
Rozalina G. McCoy,
Jennifer Mason,
Steven A. Smith,
Nilay D. Shah,
Brian T. Denton
Publication year - 2014
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc13-1901
Subject(s) - medicine , glycemic , type 2 diabetes , metformin , diabetes mellitus , population , sulfonylurea , insulin , endocrinology , environmental health
While metformin is generally accepted as the first-line agent in treatment of type 2 diabetes, there are insufficient evidence and extensive debate about the best second-line agent. We aimed to assess the benefits and harms of four commonly used antihyperglycemia treatment regimens considering clinical effectiveness, quality of life, and cost.

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