Glucagon-Like Peptide 1 Attenuates the Acceleration of Gastric Emptying Induced by Hypoglycemia in Healthy Subjects | Zendy

Mark P. Plummer | Zendy; Karen L. Jones | Zendy; Chris E. Annink | Zendy; Caroline E. Cousins | Zendy; Juris J. Meier | Zendy; Marianne J. Chapman | Zendy; Michael Horowitz | Zendy; Adam M. Deane | Zendy

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Glucagon-Like Peptide 1 Attenuates the Acceleration of Gastric Emptying Induced by Hypoglycemia in Healthy Subjects

Author(s) -

Mark P. Plummer,

Karen L. Jones,

Chris E. Annink,

Caroline E. Cousins,

Juris J. Meier,

Marianne J. Chapman,

Michael Horowitz,

Adam M. Deane

Publication year - 2014

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc13-1813

Subject(s) - gastric emptying , medicine , hypoglycemia , placebo , endocrinology , glucagon , insulin , glucose clamp technique , diabetes mellitus , glucagon like peptide 1 , crossover study , type 2 diabetes , pancreatic hormone , stomach , insulin resistance , alternative medicine , pathology

Exogenous GLP-1 slows gastric emptying in health and diabetes leading to diminished glycemic excursions. Gastric emptying is markedly accelerated by hypoglycemia. The primary objective was to determine whether GLP-1 attenuates the acceleration of gastric emptying induced by hypoglycemia.

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