Total and Cause-Specific Mortality by Elevated Transferrin Saturation and Hemochromatosis Genotype in Individuals With Diabetes: Two General Population Studies | Zendy

Christina Ellervik | Zendy; Thomas MandrupPoulsen | Zendy; Anne TybjærgHansen | Zendy; Børge G. Nordestgaard | Zendy

Open Access

Total and Cause-Specific Mortality by Elevated Transferrin Saturation and Hemochromatosis Genotype in Individuals With Diabetes: Two General Population Studies

Author(s) -

Christina Ellervik,

Thomas MandrupPoulsen,

Anne TybjærgHansen,

Børge G. Nordestgaard

Publication year - 2013

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc13-1198

Subject(s) - medicine , hazard ratio , diabetes mellitus , hemochromatosis , transferrin saturation , population , type 2 diabetes , gastroenterology , hereditary hemochromatosis , genotype , proportional hazards model , endocrinology , confidence interval , anemia , iron deficiency , genetics , biology , environmental health , gene

Mortality is increased in patients with hereditary hemochromatosis, in individuals from the general population with increased transferrin saturation (TS), and also in patients with type 1 diabetes and increased TS from a highly specialized diabetes clinic. Thus, we have recommended targeted screening for TS in specialized diabetes clinics. Whether mortality is also increased in individuals from the general population with diabetes and increased TS is unknown.

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