Response to Comment on: Besser et al. Lessons From the Mixed-Meal Tolerance Test: Use of 90-Minute and Fasting C-Peptide in Pediatric Diabetes. Diabetes Care 2013;36:195–201
Author(s) -
Beverley M. Shields,
William Henley,
Rachel Besser,
Andrew T. Hattersley,
Johnny Ludvigsson
Publication year - 2013
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc13-0609
Subject(s) - medicine , diabetes mellitus , meal , test (biology) , gerontology , family medicine , endocrinology , paleontology , biology
We thank Dr. Chaudhary and colleagues (1) for their interest in our article (2). The authors raise some statistical questions about the analysis of the effects of age at diagnosis and fasting C-peptide on the time to insulin deficiency. We are happy that our analysis and results are correct but would like to clarify the assumptions made and to highlight a minor issue with the presentation of these results in Fig. 3 of our article.The authors point out that Kaplan-Meier graphs should begin from unity at time zero (diagnosis). We can confirm that this was the case in our analysis, but we agree that …
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