Response to Comment on: Satoh-Asahara et al. Highly Purified Eicosapentaenoic Acid Increases Interleukin-10 Levels of Peripheral Blood Monocytes in Obese Patients With Dyslipidemia. Diabetes Care 2012;35:2631–2639 | Zendy

Noriko SatohAsahara | Zendy; Akira Shimatsu | Zendy; Hiromichi Wada | Zendy; Takayoshi Suganami | Zendy; Koji Hasegawa | Zendy; Yoshihiro Ogawa | Zendy

Open Access

Response to Comment on: Satoh-Asahara et al. Highly Purified Eicosapentaenoic Acid Increases Interleukin-10 Levels of Peripheral Blood Monocytes in Obese Patients With Dyslipidemia. Diabetes Care 2012;35:2631–2639

Author(s) -

Noriko SatohAsahara,

Akira Shimatsu,

Hiromichi Wada,

Takayoshi Suganami,

Koji Hasegawa,

Yoshihiro Ogawa

Publication year - 2013

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc13-0376

Subject(s) - eicosapentaenoic acid , medicine , docosahexaenoic acid , dyslipidemia , polyunsaturated fatty acid , diabetes mellitus , type 2 diabetes , gastroenterology , endocrinology , fatty acid , biochemistry , chemistry

We appreciate the comments made by Professor Nonogaki regarding our article entitled “Highly Purified Eicosapentaenoic Acid Increases Interleukin-10 Levels of Peripheral Blood Monocytes in Obese Patients With Dyslipidemia,” and we sincerely respond to his comments here (1).First, Professor Nonogaki described a recent systemic review and meta-analysis demonstrating that supplementation with omega-3 polyunsaturated fatty acids is not associated with a lower risk of all-cause mortality or major coronary events (MCE). However, the median dose of omega-3 including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in 20 trials referenced by this meta-analysis was 1.0 g/day, and the median dose of EPA in these 20 trials was only 0.46 g/day. However, …

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