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We read with great interest the article by Torres-Mejia et al. (1) showing that moderate-intensity physical activity can substantially ameliorate the increased risk of breast cancer (BC) in diabetic women. In addition, higher serum levels of C-peptide, IGF-1, and IGF-1 binding protein 3 (IGFBP3) were found to increase BC risk in premenopausal women. The finding is important because there is little evidence on physical activity and BC risk in diabetic women. In this letter, we would like to draw attention to several aspects.First, compared with the least active women, a …

diabetes care

Comment on: Torres-Mejía et al. Moderate-Intensity Physical Activity Ameliorates the Breast Cancer Risk in Diabetic Women. Diabetes Care 2012;35:2500–2502