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We very much appreciate the article by Dr. Bernstein regarding callus debridement and, in fact, agree with him in that calluses and their treatment are not trivial affairs in the patient with diabetes, neuropathy, and peripheral artery disease (1). Just as we have all seen devastating consequences with coumadin therapy or colitis caused by antibiotic dosing, callus debridement in the wrong hands can lead to significant morbidity too. This is increasingly true as our formerly mainly neuropathic patients are now increasingly often neuroischemic (2). We would argue, though, that—just as with coumadin or colitis—the lack of treatment can lead to even more devastation. In terms of calluses, …

Comment on: Bernstein. Reducing Foot Wounds in Diabetes. Diabetes Care 2013;36:e48