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Richter et al. (1) report an association between serum levels of the adipokine progranulin and chronic kidney disease (CKD) and demonstrate higher progranulin levels with deteriorating renal function—the highest progranulin levels being observed in stage 5 of CKD. The authors conclude that impaired renal clearance might account …

Comment on: Richter et al. Serum Levels of the Adipokine Progranulin Depend on Renal Function. Diabetes Care 2013;36:410–414