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Pan et al. (1) recently concluded a meta-analysis on the relationship between depression and metabolic syndrome (MetS), targeting 29 cross-sectional and 11 cohort studies. They calculated the pooled odds ratio using random-effects models. Then, they speculated the mechanism of the cause-effect relationship between the two.But before accepting their comments, I want to point out the fragility of this meta-analysis. …

diabetes care

Comment on: Pan et al. Bidirectional Association Between Depression and Metabolic Syndrome: A Systematic Review and Meta-analysis of Epidemiological Studies. Diabetes Care 2012;35:1171–1180