Response to Comment on: Gruden et al. Severe Hypoglycemia and Cardiovascular Disease Incidence in Type 1 Diabetes: The EURODIAB Prospective Complications Study. Diabetes Care 2012;35:1598–1604 | Zendy

Gabriella Gruden | Zendy; Federica Barutta | Zendy; Paolo Cavallo Perin | Zendy; Graziella Bruno | Zendy

Open Access

Response to Comment on: Gruden et al. Severe Hypoglycemia and Cardiovascular Disease Incidence in Type 1 Diabetes: The EURODIAB Prospective Complications Study. Diabetes Care 2012;35:1598–1604

Author(s) -

Gabriella Gruden,

Federica Barutta,

Paolo Cavallo Perin,

Graziella Bruno

Publication year - 2012

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc12-1500

Subject(s) - medicine , diabetes mellitus , epidemiology , incidence (geometry) , hypoglycemia , disease , intensive care medicine , type 2 diabetes , united kingdom prospective diabetes study , prospective cohort study , pediatrics , family medicine , endocrinology , physics , optics

We thank Dr. Gimenez and Dr. Conget for their comments (1) on our article, recently published in Diabetes Care (2). We acknowledge that our study has several limitations, as it was stated in the discussion, and that the “null hypothesis” should be accepted with caution. In addition, we agree that further large prospective epidemiological studies in type 1 diabetic patients are needed to offer a definite answer on this relevant topic. On the other hand, we believe that existing clinical/epidemiological data …

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