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We read the commentary by Rayner, Talley, and Horowitz (1) with much interest, since it raised the possibility of confounding by sociodemographic factors in our findings. We would like to clarify that our study on elderly Latinos (2) controlled for potential confounding of the relationship between chronic infections and diabetes by sociodemographic factors. We controlled for age, sex, and education level, which is an important maker of socioeconomic status in elderly whose income may not necessarily reflect wealth postretirement. Rayner, Talley, and Horowitz point to …

Comment on: Rayner et al. Stomach Bugs and Diabetes: An Astounding Observation or Just Confounding? Diabetes Care 2012;35:463–464