Response to Comment on: Ellervik et al. Elevated Transferrin Saturation and Risk of Diabetes: Three Population-Based Studies. Diabetes Care 2011;34:2256-2258 | Zendy

Christina Ellervik | Zendy; Thomas MandrupPoulsen | Zendy; Henrik Birgens | Zendy; Børge G. Nordestgaard | Zendy

Open Access

Response to Comment on: Ellervik et al. Elevated Transferrin Saturation and Risk of Diabetes: Three Population-Based Studies. Diabetes Care 2011;34:2256-2258

Author(s) -

Christina Ellervik,

Thomas MandrupPoulsen,

Henrik Birgens,

Børge G. Nordestgaard

Publication year - 2012

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc12-0382

Subject(s) - medicine , diabetes mellitus , transferrin saturation , population , endocrinology , environmental health , iron deficiency , anemia

We thank Conway for her comment (1) on our article in Diabetes Care (2) on the risk of diabetes associated with elevated transferrin saturation levels in two follow-up studies (risk as hazard ratios and exposure preceding disease) and a case-control study (risk as odds ratio) with neither study being cross-sectional.We agree with Conway that the pathophysiology of diabetes is complex. We acknowledge that elevated cellular iron concentrations in insulin-sensitive tissue and the pancreatic …

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