Comment on: Jeon et al. Helicobacter pylori Infection Is Associated With an Increased Rate of Diabetes. Diabetes Care 2012;35:520–525 | Zendy

Stergios A. Pοlyzos | Zendy; Jannis Kountouras | Zendy; Christos Zavos | Zendy; Georgia Deretzi | Zendy

Open Access

Comment on: Jeon et al. Helicobacter pylori Infection Is Associated With an Increased Rate of Diabetes. Diabetes Care 2012;35:520–525

Author(s) -

Stergios A. Pοlyzos,

Jannis Kountouras,

Christos Zavos,

Georgia Deretzi

Publication year - 2012

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc12-0248

Subject(s) - medicine , diabetes mellitus , helicobacter pylori , helicobacter pylori infection , helicobacter infections , gastroenterology , endocrinology

Jeon et al. (1) stated that infectious agents might have an impact on cardiovascular disease (CVD) and metabolic syndrome, potentially mediated by increased inflammatory markers, including C-reactive protein (CRP) and interleukin (IL)-6. However, epidemiological studies investigating the impact of pathogen burden on diabetes have been limited; cross-sectional studies examining systemic pathogens and insulin resistance (IR) or prevalent diabetes have produced equivocal findings, and Helicobacter pylori infection ( Hp -I) shows no association with IR or prevalent diabetes.We previously conducted a systematic review summarizing the epidemiological evidence regarding the association between Hp -I and IR quantitative-only indices (2). A positive association between Hp -I and homeostasis model assessment of insulin resistance …

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