Antepartum Oral Disposition Index as a Predictor of Glucose Intolerance Postpartum

Although women with gestational diabetes mellitus (GDM) have an increased subsequent risk for diabetes, the diabetic risk might be heterogeneous because the degree of abnormal glucose metabolism varies. The glucose tolerance status in pregnancy is related with postpartum prediabetes or diabetes, whereas studies on the antepartum factors associated with dysglycemia postpartum are limited (1,2). Women with GDM should be screened for diabetes postpartum; however, some miss the follow-up for the glucose surveillance.β-Cell function contributes to the development of glucose intolerance, and the oral glucose tolerance test (OGTT)-derived measures for β-cell function (i.e., oral disposition index [DIo]) seem to be predictive of developing diabetes (3). Likewise, the DIo during pregnancy might have potential to predict glucose intolerance postpartum. Therefore, we investigated the relation …