Possible Influence of Ileal Neobladder on Assessment of Urinary C-peptide | Zendy

Takahiro Zenda | Zendy; Masaji Miyamoto | Zendy; T Misaki | Zendy; Shuichi Kaneko | Zendy

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Possible Influence of Ileal Neobladder on Assessment of Urinary C-peptide

Author(s) -

Takahiro Zenda,

Masaji Miyamoto,

T Misaki,

Shuichi Kaneko

Publication year - 2012

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc11-2073

Subject(s) - medicine , urinary system , urology , diabetes mellitus , urinary diversion , endocrinology , cystectomy , bladder cancer , cancer

Urinary C-peptide (UCP) is one of the most popular indicators of insulin secretion by pancreatic β-cells (1,2). However, there are no previous reports discussing the relationship between UCP and neobladder, a new, reconstructed bladder using the ileum after radical cystectomy (3,4). We report a patient with neobladder in whom, among parameters of endogenous insulin production, only the 24-h UCP level was extremely decreased.A 61-year-old Japanese man with diabetes and atrial fibrillation was hospitalized because of left-sided hemiplegia and motor aphasia caused by thrombotic cerebral infarction. The patient had undergone bladder reconstruction with 66 cm of the ileum after radical cystectomy as the result of cancer 10 years ago. Only a lineal operation scar …

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