A Case of Insulin-Dependent Diabetes Associated With Enteroviral Infections

Enteroviruses have been reported to be a potential trigger of the development of type 1 diabetes by inducing β-cell autoantibodies and by directly destroying β-cells (1). Although the precise underlying mechanisms for enterovirus-mediated development of diabetes remain unknown, the systematic review and meta-analysis of observational molecular studies demonstrates a clinically significant association between enteroviral infections detected by molecular methods and type 1 diabetes (2). Here we report a case of juvenile-onset insulin-dependent diabetes resulting from various enteroviral infections.A 20-year-old man was referred and admitted to our hospital because of a penile inflammation, suffering from general fatigue, and body weight loss for 2 weeks in March 2011. He had a high fever (38–39°C) at 2 weeks before the admission. …