Comment on: Hellemons et al. Initial Angiotensin Receptor Blockade–Induced Decrease in Albuminuria Is Associated With Long-Term Renal Outcome in Type 2 Diabetic Patients With Microalbuminuria: A Post Hoc Analysis of the IRMA-2 Trial. Diabetes Care 2011;34:2078–2083 | Zendy

Mayer B. Davidson | Zendy

Open Access

Comment on: Hellemons et al. Initial Angiotensin Receptor Blockade–Induced Decrease in Albuminuria Is Associated With Long-Term Renal Outcome in Type 2 Diabetic Patients With Microalbuminuria: A Post Hoc Analysis of the IRMA-2 Trial. Diabetes Care 2011;34:2078–2083

Author(s) -

Mayer B. Davidson

Publication year - 2011

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc11-1772

Subject(s) - microalbuminuria , irbesartan , medicine , albuminuria , post hoc analysis , diabetes mellitus , angiotensin receptor , type 2 diabetes , urology , endocrinology , angiotensin ii , diabetic nephropathy , blood pressure

Hellemons et al. (1) in a post hoc analysis of the Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria (IRMA)-2 trial provocatively showed that the initial reduction of microalbumiuria with an angiotensin receptor blocker (ARB) was independently associated with renoprotection (i.e., independent of blood pressure changes). Antihypertensive medication was removed for a 3-week run-in …

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