Comment on: Hernandez et al. Patterns of Glycemia in Normal Pregnancy: Should the Current Therapeutic Targets Be Challenged? Diabetes Care 2011;34:1660–1668

The article by Hernandez et al. (1) makes a useful contribution to documenting normoglycemia in pregnancy. Although the current target glucose levels in managing gestational diabetes (GDM) are for the most part based on case-control studies, the author's statement that macrosomia still occurs if these targets are met is belied by the Maternal-Fetal Medicine Units Network report of a 7.1% large-for-gestational-age (LGA) rate when these targets are attained (2). Two more important concerns exist: the veracity of the data and using 1 SD above a weighted mean as a proposed target for glycemic control in GDM.Based on their review of data from 255 …