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Permanent neonatal diabetes (PND) is an extremely rare condition. Few cases of PND caused by pancreas-development failure have been described, and only a few genetic causes have been identified so far (1).We describe a boy with PND caused by pancreas agenesis, currently age 7 years. He is the first child of healthy, unrelated parents. He was born at 35 weeks of gestation, with severe intrauterine growth restriction (weight 1,620 g; length 45 cm). In the first day of life he developed severe hyperglycemia, and neonatal diabetes was diagnosed and treated with insulin, initially intravenously and then subcutaneously. Atrial septal defect was diagnosed in absence of …

Neonatal Diabetes Caused by Pancreatic Agenesia