Etanercept Treatment in Children With New-Onset Type 1 Diabetes: Pilot Randomized, Placebo-Controlled, Double-Blind Study | Zendy

Mike J.L. Peters | Zendy

Open Access

Etanercept Treatment in Children With New-Onset Type 1 Diabetes: Pilot Randomized, Placebo-Controlled, Double-Blind Study

Author(s) -

Mike J.L. Peters

Publication year - 2009

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc09-1372

Subject(s) - medicine , etanercept , placebo , type 2 diabetes , double blind , diabetes mellitus , randomized controlled trial , type 1 diabetes , endocrinology , alternative medicine , tumor necrosis factor alpha , pathology

I read with great interest the article by Mastrandea et al. (1) discussing the potential of etanercept in pediatric patients with newly diagnosed type 1 diabetes. The authors performed a pilot randomized, placebo-controlled, double-blind study with etanercept and found lower A1C and increased endogeneous insulin production, suggesting preservation of β-cell function. These observations are promising and certainly merit further investigation, but I feel some points of balance …

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