Changes in Serum Adiponectin Concentrations Correlate With Changes in BMI, Waist Circumference, and Estimated Visceral Fat Area in Middle-Aged General Population
Author(s) -
Yukiyoshi Okauchi,
Ken Kishida,
Tohru Funahashi,
Midori Noguchi,
Tomoko Ogawa,
Miwa Ryo,
Kohei Okita,
Hiromi Iwahashi,
Akihisa Imagawa,
Tadashi Nakamura,
Yūji Matsuzawa,
Iichiro Shimomura
Publication year - 2009
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc09-1130
Subject(s) - adiponectin , waist , medicine , endocrinology , adipose tissue , diabetes mellitus , obesity , population , metabolic syndrome , circumference , body mass index , insulin resistance , geometry , mathematics , environmental health
Adiponectin was identified as an adipocytokine in the human adipose tissue cDNA library. It has antiatherosclerotic and antidiabetic properties in experimental studies, and its blood levels are low in obesity, diabetes, cardiovascular diseases, and metabolic syndrome. Several studies have reported that weight reduction in massively obese subjects is associated with a rise in serum adiponectin (APN) concentration (1–3). However, the relationship between changes in APN and BMI, waist circumference (WC), and visceral fat accumulation (VFA) in general population has not been reported. The present study investigated 1-year change in APN (ΔAPN) in relation to changes in BMI (ΔBMI), WC …
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