HNF1B Abnormality (Mature-Onset Diabetes of the Young 5) in Children and Adolescents | Zendy

Klemens Raile | Zendy; Eva Klopocki | Zendy; Theda Wessel | Zendy; Dorothee Deiss | Zendy; Denise Horn | Zendy; Dominik Müller | Zendy; Reinhard Ullmann | Zendy; Annette Grüters | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

HNF1B Abnormality (Mature-Onset Diabetes of the Young 5) in Children and Adolescents

Author(s) -

Klemens Raile,

Eva Klopocki,

Theda Wessel,

Dorothee Deiss,

Denise Horn,

Dominik Müller,

Reinhard Ullmann,

Annette Grüters

Publication year - 2008

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc08-0920

Subject(s) - hnf1b , medicine , diabetes mellitus , abnormality , genetics , gene , homeobox , psychiatry , endocrinology , biology , gene expression

Mature-onset diabetes of the young 5 (MODY5) is characterized by a wide clinical spectrum, including diabetes and kidney disease (1–3). Associated gene defects are either mutations within HNF1B or a 1.4–1.5 Mb monoallelic deletion of chromosome 17q12 including HNF1B (4,5). Up to now, information on prevalence of MODY5 in children and adolescents with diabetes has been very limited (2). We now report prevalence of MODY5 and associated anomalies of HNF1B in a large cohort of children and adolescents with diabetes being followed at our diabetes center

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research