Open AccessImpact of Autonomic Neuropathy on Left Ventricular Function in Normotensive Type 1 Diabetic Patients: a Tissue Doppler Echocardiographic Study
Author(s) -
Per M. Humpert,
Dimitrios Oikonomou,
Michael Morcos,
Helmut F. Kuecherer,
Tobias Schilling,
Angelika Bierhaus,
Peter P. Nawroth,
Hugo A. Katus,
Grigorios Korosoglou
Publication year - 2008
Publication title -
diabetes care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.636
H-Index - 363
eISSN - 1935-5548
pISSN - 0149-5992
DOI - 10.2337/dc07-2431
Subject(s) - medicine , cardiology , diabetes mellitus , coronary artery disease , doppler imaging , autonomic function , myocardial infarction , diastole , expiration , diastolic function , type 2 diabetes , heart rate , heart rate variability , blood pressure , endocrinology , respiratory system
Data from a recent study (1) suggest that autonomic cardiovascular function (ANF) influences left ventricular (LV) diastolic function in patients with type 1 diabetes. Utilizing similar methods, including tissue Doppler imaging (TDI) and echocardiographic phase imaging (EPI) as described (2), we studied 49 type 2 diabetic patients (33 men, 16 women) with normal renal function and LV wall thickness. Five patients had a history of coronary artery disease (CAD), and none had previous myocardial infarction. Patients were screened for ANF as described (3) utilizing a standardized protocol and were divided into groups by tertiles of expiration-to-inspiration ratio (E/I) of heart rate variability (4 …
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