Insulin Resistance Is Associated With Decreased Circulating Mannan-Binding Lectin Concentrations in Women With Polycystic Ovary Syndrome | Zendy

Irina Kowalska | Zendy; José Manuel FernándezReal | Zendy; Marek Strączkowski | Zendy; Agnieszka Kozłowska | Zendy; Agnieszka Adamska | Zendy; Francisco Ortega | Zendy; Agnieszka Nikołajuk | Zendy; Monika KarczewskaKupczewska | Zendy; Sławomir Wołczyński | Zendy; Maria Górska | Zendy

Open Access

Insulin Resistance Is Associated With Decreased Circulating Mannan-Binding Lectin Concentrations in Women With Polycystic Ovary Syndrome

Author(s) -

Irina Kowalska,

José Manuel FernándezReal,

Marek Strączkowski,

Agnieszka Kozłowska,

Agnieszka Adamska,

Francisco Ortega,

Agnieszka Nikołajuk,

Monika KarczewskaKupczewska,

Sławomir Wołczyński,

Maria Górska

Publication year - 2008

Publication title -

diabetes care

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.636

H-Index - 363

eISSN - 1935-5548

pISSN - 0149-5992

DOI - 10.2337/dc07-1872

Subject(s) - polycystic ovary , mannan binding lectin , medicine , lectin , insulin resistance , diabetes mellitus , endocrinology , ovary , insulin , immunology

Insulin resistance has been described as associated with low levels of mannan-binding lectin (MBL), a protein of the innate immune system (1). The aim of the present study was to study serum MBL concentration in polycystic ovary syndrome (PCOS) in relation to insulin resistance, adiponectin, and high-sensitivity C-reactive protein (hsCRP). Insulin sensitivity, serum MBL concentration, adiponectin, hsCRP, and sex hormones were measured in 102 PCOS (34 of whom were lean and 68 overweight or obese) …

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